Clonogenic cytotoxicity testing by microdrop encapsulation

Nature, May 13 1993, vol. 363, pp. 189-190

Blane Goguen and Nancy Kedersha

Cytotoxicity is defined as the in situ measurement of cellular function in response to a toxic substance. Cytotoxicity assays are widely used in drug screening and development research to minimize the number of compounds on which expensive mammalian animal model toxicology studies are performed.

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